| Date | Opponent |
| Sunday, August 31 | at Miami |
| Saturday, September 13 | Texas A&M |
| Saturday, September 20 | Purdue |
| Saturday, September 27 | at Arkansas |
| Saturday, October 4 | Boise State |
| Saturday, October 11 | NC State |
| Saturday, October 18 | USC |
| Saturday, November 1 | at Boston College |
| Saturday, November 8 | Navy |
| Saturday, November 15 | at Pittsburgh |
| Saturday, November 22 | Syracuse |
| Saturday, November 29 | at Stanford |
2025 Notre Dame Football Schedule
